Started in June 1955, due to the efforts of a group of parents who wanted to obtain services for their children who were mentally retarded, the Niagara County Chapter of the Association for Retarded Children, (known today as Opportunities Unlimited of Niagara) was incorporated as a chapter of the New York State Association for Retarded Children (known today as NYSARC, Inc.).

The agency originally operated school programs in Niagara Falls, Lockport and North Tonawanda.  These programs provided learning and support to children with mental retardation and developmental disabilities, basic needs that they had previously been denied. 

The agency's first sheltered workshop opened in the 1960's, followed by its first community residence in the 1970's.   In 1990, the agency's name was changed to Opportunities Unlimited of Niagara to reflect the organizational philosophy of building opportunities for people with disabilities and ensuring that they be able to reach their maximum potential and independence through integration into the community.

The provision of new choices in vocational programs spurred a period of growth throughout the 1990's.  Opportunities Unlimited was aggressive and sought ways to offer innovative programs and services for consumers which focused on the 3 IP's of Inclusion, Independence, Individualization and Productivity.

August 1998, marked the start to a new era of growth for agencies serving the disabled throughout New York State with then Governor George Pataki's announcement of a five-year plan aimed at eliminating the waiting list for persons needing out-of-home residential care.   The program, named New York State CARES, plans to assist Opportunities Unlimited of Niagara with continuing its commitment toward integration of people with disabilities and offering them an opportunity for community living.

Today, Opportunities Unlimited of Niagara annually assists more than 800 people to reach goals and lead more independent lives.  Services include on-site vocational training; community-based job placement and employment support; school to work transition planning; day programming; clinical services; transportation; residential choices; supportive services such as recreation, self-advocacy and exceptional parenting programs; and service coordination to ensure that each person receives as much support as needed to become as independent as possible.